Irf2bp2 cancer

Author: camr

August undefined, 2024

WebApr 25, 2024 · The IRF2BP2 (IFN regulatory factor 2 binding protein 2) protein was identified as a nuclear protein that interacts with IFN regulatory factor 2 (IRF-2) and is an IRF-2 … WebInterferon regulatory factor 2 binding protein 2 (IRF2BP2) was originally identified as a transcriptional corepressor. However, the association between IRF2BP2 and the Hippo …

检索结果-暨南大学图书馆

WebNov 22, 2016 · IRF2BP2 is a downstream target of p53 and repressor of the cell cycle regulator NFAT1 (refs 7, 8). IRF2BP2 is fused to CDX1 as a result of the t (1;5) (q42;q32) in mesenchymal chondrosarcoma... WebIRF2BP2-NTRK1 Fusion is present in 0.02% of AACR GENIE cases, with sarcoma, NOS, breast invasive ductal carcinoma, gastric adenocarcinoma, lung adenocarcinoma, and pancreatic acinar cell carcinoma having the greatest prevalence [ 4 ]. Top Disease Cases with IRF2BP2-NTRK1 Fusion References 1. how much is the dear dollie skirt in rh

Douglas Faget - Postdoc Research Associate - LinkedIn

WebJul 29, 2024 · Program of Immunology and Tumor Biology, Brazilian National Cancer Institute (INCA), Rio de Janeiro, RJ, Brazil. 2. Division of Signaling and Gene Expression, La … WebJul 29, 2024 · Translocations and mutations in the human irf2bp2gene have been observed in various cancers including primary central nervous system lymphoma (Pall & Hamilton, 2008), multiple myeloma (Ni et al.,2012), mesenchymal chondrosarcoma (Nyquist et al.,2012) and acute promyelocytic leukemia (Yin et al.,2015), emphasizing the importance … WebSep 25, 2015 · IRF2BP2 is required for the expression of the anti-inflammatory transcription factor Krüppel-like factor 2 (KLF2). Restoring KLF2 in IRF2BP2-deficient macrophages … how much is the dear dollie corset

Expression of IRF2BP2 in cancer - Summary - The Human Protein …

IRF2BP2 Gene - GeneCards I2BP2 Protein I2BP2 Antibody

WebApr 8, 2024 · The researchers discovered Richter syndrome-specific somatic driver mutations in genes including IRF2BP2, SRSF1, B2M, DNMT3A, and CCND3. They also found recurrent copy-number alterations beyond del(9p21)(CDKN2A/B), whole-genome duplication and chromothripsis, which they confirmed in 45 independent Richter syndrome cases and … WebApr 29, 2024 · The IRF2BP2 protein is found in different organisms and has been described as ubiquitously expressed in normal and tumor cells and tissues, indicating a possible role for this transcriptional... how much is the death tax 2021WebJun 15, 2024 · Recently, interferon regulatory protein 2 binding protein 2 ( IRF2BP2) emerged as a new RARA partner and was studied by next-generation RNA-sequencing analysis. IRF2BP2 has also been involved in other solid tumors [ 2, 3, 4 ]. Fig. 1 A Wright-Giemsa staining of abnormal promyelocytes at diagnosis. B Alpha naphthol acetate … how do i get a receipt from american airlines

"WebSep 20, 2024 · In this study, we uncovered the clinical significance of IRF2BP2 in suppressing hepatocellular carcinogenesis. We showed that IRF2BP2, a direct target repressed by the Yes-associated protein … " - Irf2bp2 cancer

Irf2bp2 cancer

Clinicopathologic features of kinase fusion-related thyroid …

WebJul 6, 2024 · We identified the immune modulator IRF2BP2 as a selective AML dependency. We validated AML cell dependency on IRF2BP2 with genetic and protein degradation … WebSep 25, 2015 · In a recent issue of Circulation Research, Chen et al report that IRF 2–binding protein 2 (IRF2BP2) is a novel regulator of macrophage inflammation and lipid homeostasis that acts by maintaining anti-inflammatory transcription factor Krüppel-like factor 2 (KLF2) expression, therefore reducing susceptibility to atherosclerosis 6 ( Figure 2 ).

Did you know?

WebIRF2BP2 INFORMATION. Proteini. Full gene name according to HGNC. Interferon regulatory factor 2 binding protein 2. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. IRF2BP2 (IRF-2BP2) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). WebJul 30, 2024 · The levels of the co-transcriptional regulator IRF2BP2 (Interferon Regulatory Factor-2 Binding Protein-2) decrease with T cell activation and, when ectopically expressed, it reduces T cell proliferation. To further characterize the function of IRF2BP2 in T cell responses in vivo, we generated a conditional transgenic knock-in mouse that …

WebSep 20, 2024 · IRF2BP2 stabilized VGLL4 protein and repressed tumor progression via the inactivation of YAP-TEAD4 complex in liver cancer (41). In contrast, IRF2BP2 repressed … WebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of …

WebSep 20, 2024 · The conserved Hippo pathway regulates organ size, tissue homeostasis, and tumorigenesis. Interferon regulatory factor 2 binding protein 2 (IRF2BP2) was originally … WebNov 22, 2016 · IRF2BP2 is a downstream target of p53 and repressor of the cell cycle regulator NFAT1 (refs 7, 8). IRF2BP2 is fused to CDX1 as a result of the t (1;5) (q42;q32) …

National Center for Biotechnology Information

WebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... To access cancer specific RNA and … how do i get a recovery key for icloudWebExpression of IRF2BP2 (IRF-2BP2) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. ... BREAST CANCER CARCINOID CERVICAL CANCER COLORECTAL CANCER ENDOMETRIAL CANCER GLIOMA HEAD AND NECK CANCER LIVER CANCER LUNG CANCER LYMPHOMA. how do i get a red cardWebMar 29, 2024 · IRF2BP2 is a novel ischemia-induced coactivator of VEGFA expression that may contribute to revascularization of ischemic cardiac and skeletal muscles. IRF2BP2 … how much is the dear dolly sethttp://english.cemcs.cas.cn/news/202411/t20241120_252214.html how do i get a redemption statement from hsbcWeb开馆时间：周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 how do i get a recording contractWebJan 1, 2024 · For example, IRF2BP2 is confirmed to be upregulated in gastric cancer, and its deficiency impedes cell proliferation and epithelial-mesenchymal transition. 42 IRF2BP2 represses liver cancer progression via stabilizing VGLL4 and further enhancing VGLL4’s inhibitory effects on Hippo pathway. 43 In our study, we discovered that IRF2BP2 might … how do i get a redress numberWeb癌症免疫疗法是生物医学界目前最热门的领域之一。近日，发表在《科学》杂志上的一项研究中，科学家们发现了一种参与肿瘤免疫逃逸行为的关键蛋白，它与“赫赫有名”的PD-L1蛋白的表达密切相关。这一名为Cdk5的关键蛋白及其相关信号通路有望成为免疫疗法的新靶点。 how do i get a redress number for travel