WebMetal complexes with N-alkylphenothiazines are biological active compounds with different antimicrobial activities and cytotoxic effect against tumor cell lines. The large field of … WebApr 12, 2024 · If there is one or more donor atoms present near to the carbonyl group, the chalcones can form chelate metal complexes. Chalcone derivatives can form complexes …
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WebWe tested the inhibitory action of some new metal complexes of phenothiazines on megacin encoding bacterial gene induced by mitomycin-C as an example of 'SOS induction' and on efflux pump of mouse lymphoma cells. The interaction of compounds to DNA was measured by thermal stability of DNA. WebAcridine and Phenothiazine Based Photosensitizers . by Beth Wilson Under the Direction of Dr. Kathryn B. Grant ABSTRACT Photosensitizing molecules and/or metal complexes that interact with DNA via intercalation and groove binding have potential applications as molecular structural probes, as footprinting reagents and in photodynamic therapeutics. camhs outreach jobs
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WebApr 2, 1996 · Phenothiazine derivatives substituted in the 2, and 10 positions belong to a big group of tricyclic aromatic compounds. They are in extensive use in psychiatry as tranquilizers, and neuroleptics. Due to their characteristic structure they exhibit many valuable analytical properties. WebAug 10, 2024 · Tris (phenanthroline) complexes of ruthenium (II), cobalt (III), and rhodium (III) are octahedral, substitutionally inert complexes, and as a result of this coordinative saturation the complexes bind to double-helical DNA through a mixture of noncovalent interactions. Tris (phenanthroline) metal complexes bind to the double helix both by ... WebJul 13, 2024 · Metal–ligand complexes undergo diverse charge-transfer processes when stimulated by light or electric fields. This Perspective describes how these processes can be exploited in photosensitizers ... camhs ot